Melinta Therapeutics Launches New Antibiotic Stewardship Program to Combat Growing Threat of Antimicrobial Resistance
The Melinta Antimicrobial Stewardship Program will further Melinta’s leadership in the fight against the global public health threat of antimicrobial resistance (AMR) by implementing comprehensive measures and metrics within the company’s commercial, manufacturing and research and development operations designed to promote the responsible and sustainable use of its current and future antibiotic portfolio.
Melinta will take concrete steps as part of the program, including conducting AMR surveillance efforts such as post-marketing susceptibility testing and real-world use registries; implementing stewardship-focused promotional standards; evaluating economic models to support the responsible and sustainable use of its products; and undertaking educational programming with healthcare providers.
In addition, Melinta will continue to work with its manufacturing partners to develop and implement environmental risk-management strategies for minimizing the impact of antibiotic discharge. Within its R&D operations, the company will continue to focus on the development of breakthrough antibiotics for bacterial “superbugs” through its ESKAPE Pathogen Program while advancing the development of its existing portfolio of antibiotics.
Melinta will host an expert panel session today at the 21st Annual MAD-ID Meeting, the leading industry summit focused on antimicrobial stewardship and patient care, to introduce the program and discuss opportunities to leverage collective expertise to combat AMR.
“Antimicrobial resistance is an urgent global health threat and, as the industry’s largest pure-play antibiotics company, Melinta is committed to demonstrating leadership in the fight against it,” said
The launch of Melinta’s new program is the first step in the company’s expanded effort to play a leading role the fight against antimicrobial resistance, and builds on the company’s existing leadership, including its position as a signatory company to the Industry Declaration on AMR at the
Each year in
At the same time, 5.7 million people globally die each year from treatable infections because they lack access to effective antimicrobials.ii
Resistant infections add significant costs to the U.S. healthcare system as a result of prolonged and/or costlier treatments, extended hospital stays and additional doctor visits. Studies estimate that antibiotic resistance in the U.S. adds approximately
Today, the incidence of resistant strains of dangerous pathogens is on the rise, with many microbes resistant to more than one drug (multidrug-resistant or MDR), others resistant to most drugs (extensively drug-resistant or XDR), and some resistant to all known drugs (pan-resistant or PDR).
The use of antibiotics is the single most important factor leading to antibiotic resistance around the world. Antibiotics are among the most commonly prescribed drugs used in human medicine. However, up to 50 percent of all the antibiotics prescribed for people are not needed or are not optimally effective as prescribed.iv
About Melinta Therapeutics
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Risks and uncertainties for Melinta include, but are not limited to: the fact that we have incurred significant operating losses since inception and will incur continued losses for the foreseeable future; our limited operating history; our need for future capital; uncertainties of cash flows and inability to meet working capital needs as well as other milestone, royalty and payment obligations; the fact that our independent registered public accounting firm’s report on the Company’s 2016 and 2017 financial statements contains an explanatory paragraph that states that the our recurring losses from operations and our need to obtain additional capital raises substantial doubt about our ability to continue as a going concern; our substantial indebtedness; risks related to our commercial launches of our products and our inexperience as a company in marketing drug products; the degree of market acceptance of our products among physicians, patients, health care payors and the medical community; the pricing we are able to achieve for our products; failure to obtain and sustain an adequate level of reimbursement for our products by third-party payors; inaccuracies in our estimates of the market for and commercialization potential of our products; failure to maintain optimal inventory levels to meet commercial demand for any of our products; risks that our competitors are able to develop and market products that are preferred over our products; our dependence upon third parties for the manufacture and supply of our marketed products; failure to achieve the benefits of our recently completed transactions with Cempra and The
Other risks and uncertainties are more fully described in our Annual Report on Form 10-K for the year ended December 31, 2017, and in other filings that Melinta makes and will make with the SEC. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. The statements made in this press release speak only as of the date stated herein, and subsequent events and developments may cause our expectations and beliefs to change. While we may elect to update these forward-looking statements publicly at some point in the future, we specifically disclaim any obligation to do so, whether as a result of new information, future events or otherwise, except as required by law. These forward-looking statements should not be relied upon as representing our views as of any date after the date stated herein.
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Source: Melinta Therapeutics